World Journal of Dentistry

Register      Login

VOLUME 2 , ISSUE 1 ( January-March, 2011 ) > List of Articles

CASE REPORT

Langerhans Cell Histiocytosis

S Jayachandran, N Balaji

Citation Information : Jayachandran S, Balaji N. Langerhans Cell Histiocytosis. World J Dent 2011; 2 (1):57-62.

DOI: 10.5005/jp-journals-10015-1055

Published Online: 01-06-2012

Copyright Statement:  Copyright © 2011; The Author(s).


Abstract

Langerhans cell histiocytosis (LCH) is rare unique disorder of the reticuloendothelial system characterized by an abnormal proliferation of histiocytes and eosinophilic leukocytes. Lichtenstein gave the term Histiocytosis X in 1953 to include three clinical varieties; Eosinophilic granuloma, Hand-Schüller-Christian disease and Letterer-Siwe disease, which shared some common histologic features and clinical findings. In 1973, the term LCH was introduced as an alternative to histiocytosis X. LCH may manifest orally with single or multiple lesions of the alveolar or basal bone, ulcerated mucosal lesions accompanied by adenopathies and/or periodontal lesions, presenting gingival inflammation, bleeding, recession, necrosis, mobility of teeth and premature loss of teeth. Herewith, we report a case of LCH in a 45-year-old male with a characteristic oral and radiological findings. The purpose of this case report is to highlight the unique and rare presentation of oral and multiple skeletal involvement of Langerhans cell histiocytosis.


PDF Share
  1. Langerhans cell histiocytosis: Literature review and descriptive analysis of oral manifestations. Med Oral Patol Oral Cir Bucal 2009 May 1;14(5):E222-28.
  2. Langerhans cell histiocytosis in the maxillofacial area in adults: Report of three cases. Med Oral Patol Oral Cir Bucal 2007;12:E145-50.
  3. Oral Langerhans cell histiocytosis. Journal of Cranio-Maxillofacial Surgery 2002;30:91-96.
  4. Langerhans cell histiocytosis involving maxilla and mandible. Journal of Dentistry, Tehran University of Medical Sciences, Tehran, Iran 2009;6(2).
  5. Langerhans’ cell disease: A case report JIAOMR 1999;10(1).
  6. Langerhans cell histiocytosis in a periapical cyst: A wolf in a sheep's clothing? Journal of the Tennessee Dental Association 88-84.
  7. Spontaneously regressed langerhans cell histiocytosis of lymphnodes in an elderly patient. The Japanese Society of Internal Medicine (DOI:10.2169/internalmedicine.46.0356).
  8. Diagnostic confirmation of Langerhans cell histiocytosis of the jaws with CD1a immunostaining: A Case Report. J Oral Maxillofac Surg 2003;61:118-22.
  9. Treatment for localized Langerhans’ cell histiocytosis of the maxilla by corticosteroid injection: A case report. Oral Science International May 2007;59-62.
  10. Langerhans’ cell histiocytosis in a six-yearold child. Indian J Dermatol Venereol Leprol March-April 2007;73(2).
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.