Citation Information :
Badran MM, Elagamy RA. Evaluation of Different Pulpotomy Agents Used for Treatment of Immature Permanent Molars: A Randomized Clinical Trial. World J Dent 2024; 15 (2):133-140.
Aim: The present study was performed to assess and compare the effectiveness of pulpotomy agents, namely calcium hydroxide, biodentine, and platelet-rich fibrin (PRF), in the treatment of immature permanent molars in children aged 7–10 years.
Materials and methods: A total of 28 children (45 molars) who underwent pulpotomy were assigned at random to one of three groups—calcium hydroxide, biodentine, or PRF. At 3, 6, 9, 12, and 18 months, postoperatively, the patients underwent clinical and preoperative radiographic evaluations utilizing digital periapical radiography and cone beam computed tomography (CBCT).
Results: There were no statistically significant changes observed in any of the groups during the 18-month follow-up period. At 18 months, the clinical success rates for calcium hydroxide, biodentine, and PRF were 86.7, 100, and 93.3%, respectively. Radiographic analysis of the root lengths of the three groups did not identify any significant variations that were statistically significant.
Conclusion: Both biodentine and PRF can be considered a substitute for calcium hydroxide as pulp medicaments after pulpotomy of immature permanent molars.
Clinical significance: The clue for the future about treating permanent molars with immature roots. It is recommended to use PRF as a great oral tissue-derived stem cell substitute for calcium hydroxide.
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