Citation Information :
Gunti N, Prathigudupu RS, Prasad LK, Gavarraju DN, Chakravarthi P, Chunduru PS, Musunuri RL. Evaluating the Efficacy of Transresveratrol in Extraction Socket of Impacted Mandibular Third Molar: A Double-blind Study. World J Dent 2023; 14 (10):869-876.
Aim: This study aimed to evaluate the effect of transresveratrol on postextraction complications, including pain, swelling, and alveolar bone density.
Materials and methods: A total of 10 extraction sockets were included in this study based on specific criteria. The sockets were randomly divided into two groups—group I received transresveratrol packed in a collagen membrane, while group II received collagen membrane alone. Pain, swelling, and alveolar bone density were assessed. Data entry and analysis were performed using Microsoft (MS) Excel and Statistical Package for the Social Sciences (SPSS) version 22 software. Statistical analysis included mean, standard deviation, proportions, and the independent t-test. A p-value of <0.05 was considered statistically significant.
Results: The mean age of the study population was 25.2 ± 1.64, with 60% males and 40% females. Comparison of pain and swelling between the two groups revealed significant differences on days 1, 3, and 7 (p < 0.05). However, the comparison of alveolar bone density on cone-beam computed tomography (CBCT) systems after 3 months showed differences but was not statistically significant (p = 0.44).
Conclusion: This study concludes that using transresveratrol has a beneficial effect on postextraction swelling, pain, and alveolar bone density.
Clinical significance: The findings of this study suggest that incorporating transresveratrol into the treatment of mandibular third molar extractions may help reduce postoperative complications such as swelling and pain. However, further research is needed to evaluate its impact on alveolar bone density fully.
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