Aim: The aim of this study was to compare clinical and occlusal patterns in patients with and without periodontitis using the T-scan software. Materials and methods: A total of 30 healthy subjects and 30 subjects with periodontal disease were recruited for this study. A T-scan analysis was done for all these patients before any intervention, and the force distribution on each side, first contact, maximum biting force, forces at maximum intercuspation, and time taken for occlusion and disocclusion were recorded for all patients. Clinical parameters, such as pocket depth, clinical attachment level, and gingival index, were also recorded. Results: Chi-squared tests reveal no significant relationship between occlusal stresses and pocket depth or clinical attachment levels (p > 0.05). The relationship between occlusal force and tooth type was statistically significant (p = 0.04). The maxillary posteriors had the highest occlusal forces, followed by the mandibular posteriors. There was no significant difference between right and left force distribution between healthy and periodontitis groups (p > 0.05); however, a significant difference was observed in occlusion and disocclusion time (p = 0.042 and 0.000, respectively). Conclusion: T-scan system is useful in the diagnosis, progression, and severity of periodontal disease, the distribution of deleterious eccentric forces that lead to periodontal destruction. The correlation of these forces to the location and type of tooth was seen to be of clinical significance. Clinical significance: The physiologically occurring repair and remodeling of forces directed onto the masticatory system components is critical, as disruptions in the physiological functioning of the masticatory system can cause periodontitis, which can lead to tooth loss. T-Scan is a software that analyzes occlusion in various aspects such as bite forces, force distribution, and time is taken for disocclusion; these readings can be taken in centric, protrusive, and laterotrusive contact in real-time, aiding the clinician in analyzing eccentric deleterious forces and treatment planning.