World Journal of Dentistry

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VOLUME 14 , ISSUE 3 ( March, 2023 ) > List of Articles


Evaluation of the Efficacy of Root Surface Biomodification Agents on Periodontal Regeneration: An SEM Study

Mohammad Jalaluddin, Shruti Shivakumar, Soniya Hatila, KV Santhosh, Thara Chandran, Konsam Bidya Devi

Keywords : Periodontal diseases, Periodontal regeneration, Root Planing, Root surface biomodification, Scaling

Citation Information : Jalaluddin M, Shivakumar S, Hatila S, Santhosh K, Chandran T, Devi KB. Evaluation of the Efficacy of Root Surface Biomodification Agents on Periodontal Regeneration: An SEM Study. World J Dent 2023; 14 (3):268-272.

DOI: 10.5005/jp-journals-10015-2167

License: CC BY-NC 4.0

Published Online: 05-05-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Aim: The aim of the current research was to appraise the effectiveness of three radicular surface biomodification agents on the regeneration of periodontal tissues. Materials and methods: A total of 60 human permanent mandibular premolars with a solitary root that was subjected to extraction owing to complex periodontal pathosis were chosen for the purpose of this research. Decoronation and longitudinal splitting of the sample tooth were performed to create sections that were shaped into a rectangle having estimated proportions of 4 × 2 × 1 mm employing slow-speed diamond bur beneath water irrigation. Next, the chosen teeth were allocated at random using a simple random technique into one of the following three groups—group I, application of Carisolv root biomodification agent; group II, application of ethylenediaminetetraacetic acid (EDTA) root biomodification agent; group III, application of a mixture of tetracycline isomer, acid, detergent (MTAD™) root biomodification agent. Each sample was evaluated and observed beneath the scanning electron microscope (SEM) at 1000× magnifying power to appraise alterations on the radicular surfaces. Results: Carisolv radicular biomodifiers exhibited the greatest radicular surface biomodification at 2.92 ± 0.12, in pursuit by EDTA radicular biomodifiers at 3.38 ± 0.09, finally followed by MTAD™ radicular biomodifiers at 3.52 ± 0.14. A statistically significant disparity was noted among the groups. Conclusion: The current research arrived at a conclusion that the Carisolv radicular biomodifiers exhibited the highest radicular surface modifying properties in comparison to EDTA and MTAD™ radicular biomodifiers. Clinical significance: Alterations in radicular surfaces in the surroundings of periodontal disease and the existence of periodontal pockets hamper the periodontal tissue's regenerative process. Periodontal management should thus produce a radicular surface well-suited for the cells that arbitrate repair as well as the periodontal regenerative process.

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