Citation Information :
Vellayappan R, Varghese SS. Effectiveness of Low-intensity Pulsed Ultrasound as an Adjunct to Periodontal Regenerative Therapy: A Randomized Controlled Clinical Trial. World J Dent 2022; 13 (S2):S182-S188.
Aim: This study was performed to evaluate the effectiveness of low-intensity pulsed ultrasound (LIPUS) as an adjunct to periodontal regenerative therapy [open flap debridement (OFD) with or without bone graft (BG)] in intrabony defects of chronic periodontitis patients.
Materials and methods: A total of 40 angular periodontal defect sites were included in this study by recruiting 18 systemically healthy volunteers. Sample sites were randomly allotted to four groups: group I, OFD; group II, OFD + LIPUS; group III, OFD + BG; and group IV, OFD + BG + LIPUS. The clinical parameters such as plaque index (PI), gingival sulcus bleeding index (SBI), probing depth (PD), clinical attachment loss, radiographic depth of the defect site, and alkaline phosphatase (ALP) level in gingival crevicular fluid (GCF) were analyzed.
Results: When compared between the groups, there was no significant difference in clinical and radiographic parameters at 3 and 6 months of postevaluation, whereas ALP level showed a significant increase at 6 weeks in group II and group IV when compared to other groups.
Conclusion: It can be concluded that LIPUS did not improve periodontal regeneration in terms of clinical and radiographic parameters when used as an adjunct to periodontal regenerative therapy. But it has shown the potential to increase the ALP level in GCF.
Clinical significance: There is no added clinical benefit in the short-term usage of LIPUS in periodontal therapy.
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