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VOLUME 13 , ISSUE S2 ( Supplementary Issue 2, 2022 ) > List of Articles


Effectiveness of Various Fluoride Varnishes in Arresting Cavitated Dentinal Lesion in Preschool Children: A Randomized Clinical Trial

Nagarathna Chikkanarasaiah, N Mounashree, Navin Hadadi Krishnamurthy, Umapathy Thimmegowda, B Amrutha

Keywords : Caries arrest, Cavitated dentinal lesion, Early childhood caries, Fluoride varnish, Preschool children, Silver diamine fluoride

Citation Information : Chikkanarasaiah N, Mounashree N, Krishnamurthy NH, Thimmegowda U, Amrutha B. Effectiveness of Various Fluoride Varnishes in Arresting Cavitated Dentinal Lesion in Preschool Children: A Randomized Clinical Trial. World J Dent 2022; 13 (S2):S144-S148.

DOI: 10.5005/jp-journals-10015-2156

License: CC BY-NC 4.0

Published Online: 31-12-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Aim: The aim of this randomized clinical trial was to compare the effectiveness of various fluoride varnishes in arresting cavitated dentinal lesions among preschool children. Materials and methods: Children aged 3–5 years old with at least one active cavitated dentinal carious lesion were recruited and randomly assigned into two groups as follows. Children in group I received 38% silver diamine fluoride (SDF) (FAgamin, Tedequim SRL, Argentina) application and children in group II received bifluorid 10 varnish (VOCO Bifluorid 10) application on carious lesion respectively. Lesion activity was assessed by visual-tactile examination using the World Health Organization (WHO) consumer price index (CPI) probe. Baseline and follow-up examinations were done by different examiners to collect the data. Result: Baseline and 1-week follow-up data was collected and subjected to statistical analysis using the Chi-squared test. The caries arrest rate in group I (100%) was highly significant. Conclusion: Silver diamine fluoride (SDF) was effective in arresting caries in preschool children and facilitating the early restoration of the cavitated lesion and was also helpful in instilling positive behavior in preschool children toward dental treatment. Clinical significance: Caries control methods used here are simple, noninvasive, highly efficient, cost-effective, well accepted, and can be used in all children. The results were satisfactory as cavitated lesions were restored in a short time in achieving good oral health.

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  1. Mabangkhru S, Duangthip D, Chu CH, et al. A randomized clinical trial to arrest dentin caries in young children using silver diamine fluoride. J Dent 2020;99:103375. DOI: 10.1016/j.jdent.2020.103375
  2. Duangthip D, Gao SS, Lo EC, et al. Early childhood caries among 5-to 6-year-old children in Southeast Asia. Int Dent J 2017;67(2):98–106. DOI: 10.1111/idj.12261
  3. Gao SS, Chen KJ, Duangthip D. Arresting early childhood caries using silver and fluoride products–a randomised trial. J Dent 2020;103:103522. DOI: 10.1016/j.jdent.2020.103522
  4. Tirupathi S, SVSG N,Rajasekhar S, et al. Comparative cariostatic efficacy of a novel Nano-silver fluoride varnish with 38% silver diamine fluoride varnish a double-blind randomized clinical trial. J Clin Exp Dent 2019;11(2):e105–e122. DOI: 10.4317/jced.54995
  5. Duangthip D, Fung MHT, Wong MCM, et al. Adverse effects of silver diamine fluoride treatment among preschool children. J Dent Res 2018;97(4):395–401. DOI: 10.1177/0022034517746678
  6. Gao SS, Zhang S, Mei ML, et al. Caries remineralisation and arresting effect in children by professionally applied fluoride treatment–a systematic review. BMC Oral Health 2016;16(1):1–9. DOI: 10.1186/s12903-016-0171-6
  7. Yu OY, Zhao IS, Mei ML, et al. Caries-arresting effects of silver diamine fluoride and sodium fluoride on dentine caries lesions. J Dent 2018;78:65–71. DOI: 10.1016/j.jdent.2018.08.007
  8. Pitts NB, Ismail AI, Martignon S, et al. ICCMS™ guide for practitioners and educators. King's College London 2014.
  9. Vollú AL, Rodrigues GF, Rougemount Teixeira RV, et al. Efficacy of 30% silver diamine fluoride compared to atraumatic restorative treatment on dentine caries arrestment in primary molars of preschool children: a 12-months parallel randomized controlled clinical trial. J Dent 2019;88:103165. DOI: 10.1016/j.jdent.2019.07.003
  10. Fung MHT, Duangthip D, Wong MCM, et al. Arresting dentine caries with different concentration and periodicity of silver diamine fluoride. JDR Clin Trans Res 2016;1(2):143–152. DOI: 10.1177/2380084416649150
  11. Gao SS, Duangthip D, Wong MC, et al. Randomized trial of silver nitrate with sodium fluoride for caries arrest. JDR Clin Trans Res 2019;4(2):126–134. DOI: 10.1177/2380084418818482
  12. Dos Santos VE Jr, de Vasconcelos FM, Ribeiro AG, et al. Paradigm shift in the effective treatment of caries in schoolchildren at risk. Int Dent J 2012;62(1):47–51. DOI: 10.1111/j.1875-595X.2011.00088.x
  13. Milgrom P, Horst JA, Ludwig S, et al. Topical silver diamine fluoride for dental caries arrest in preschool children: a randomized controlled trial and microbiological analysis of caries associated microbes and resistance gene expression. J Dent 2018;68:72–78. DOI: 10.1016/j.jdent.2017.08.015
  14. Clemens J, Gold J, Chaffin J. Effect and acceptance of silver diamine fluoride treatment on dental caries in primary teeth. J Public Health Dent 2018;78(1):63–68. DOI: 10.1111/jphd.12241
  15. Zhi QH, Lo EC, Lin HC. Randomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentine caries in preschool children. J Dent 2012;40(11):962–967. DOI: 10.1016/j.jdent.2012.08.002
  16. Duangthip D, Chu CH, Lo EC. A randomized clinical trial on arresting dentine caries in preschool children by topical fluorides–18 month results. J Dent 2016;44:57–63. DOI: 10.1016/j.jdent.2015.05.006
  17. Chibinski AC, Wambier LM, Feltrin J, et al. Silver diamine fluoride has efficacy in controlling caries progression in primary teeth: a systematic review and meta-analysis. Caries Res 2017;51(5):527–541. DOI: 10.1159/000478668
  18. Duangthip D, Wong MCM, Chu CH, et al. Caries arrest by topical fluorides in preschool children: 30-month results. J Dent 2018;70:74–79. DOI: 10.1016/j.jdent.2017.12.013
  19. Chu CH, Lo EC, Lin HC. Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentin caries in Chinese pre-school children. J Dent Res 2002;81(11):767–770. DOI: 10.1177/0810767
  20. Hamdy D, Giraki M, Abd Elaziz A, et al. Laboratory evaluation of the potential masking of color changes produced by silver diamine fluoride in primary molars. BMC Oral Health 2021;21(1):337. DOI: 10.1186/s12903-021-01697-8
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