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VOLUME 13 , ISSUE S1 ( Supplementary Issue 1, 2022 ) > List of Articles

ORIGINAL RESEARCH

Evaluation of Clinical and Microbiological Outcomes of Photodynamic Therapy-assisted Flap Surgery in Stages II and III, with Grades B and C Periodontitis: A Prospective Clinical Trial

Patri Krishna Chaitanya, Gautami S Penmetsa, Sruthima NVS Gottumukkala, Konathala Santosh Venkata Ramesh, Pasupuleti Mohan Kumar, Kommula Mani Meghana

Keywords : Bacterial count, Periodontitis, Photodynamic therapy, Photosensitizing agents, Polymerase chain reaction

Citation Information : Chaitanya PK, Penmetsa GS, Gottumukkala SN, Ramesh KS, Kumar PM, Meghana KM. Evaluation of Clinical and Microbiological Outcomes of Photodynamic Therapy-assisted Flap Surgery in Stages II and III, with Grades B and C Periodontitis: A Prospective Clinical Trial. World J Dent 2022; 13 (S1):S66-S71.

DOI: 10.5005/jp-journals-10015-2129

License: CC BY-NC 4.0

Published Online: 01-10-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim: To evaluate and compare the efficacy of surgical periodontal therapy (SurgPT) in conjunction with photodynamic-assisted surgery (PTAS) with SurgPT alone. Materials and methods: A total of 13 participants with stages II and III, with grades B and C periodontitis and contralateral probing pocket depths (PPD) ≥5 mm on at least two adjacent teeth, were randomly assigned to PTAS and SurgPT groups. Plaque index (PI), gingival index (GI), PPD, and clinical attachment level (CAL) were measured at baseline, 3, and 6 months. Red complex bacteria levels were measured using polymerase chain reaction (PCR) at baseline and 3 months. Results: All clinical parameters were reduced significantly in both groups. Intergroup comparison revealed that the PTAS group had a considerably higher PI and GI decrease. However, the difference in reduction of PPD and CAL was not significant at given time intervals. At 3 months, PCR evaluation showed a decrease in levels of red complex bacteria with no intergroup differences. Conclusion: Both the PTAS and SurgPT showed definitive improvement in all parameters. PTAS using indocyanine green (ICG) yielded a resolution of PI and GI, which can be attributed to the antimicrobial photodynamic therapy (PDT). Clinical significance: PTAS may be a safe alternative for systemic antibiotics in combination with SurgPT for the management of chronic periodontitis.


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