World Journal of Dentistry

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VOLUME 13 , ISSUE 4 ( July-August, 2022 ) > List of Articles

ORIGINAL RESEARCH

Nonsurgical Periodontal Therapy Ameliorates Clinical Periodontal Parameters and Glycemic Levels in GDM Patients with Periodontitis

S Ashwini, Kavitha Prasad, B K Sujani

Keywords : Clinical periodontal parameters, Gestational diabetes, Nonsurgical periodontal therapy, Periodontal disease

Citation Information : Ashwini S, Prasad K, Sujani BK. Nonsurgical Periodontal Therapy Ameliorates Clinical Periodontal Parameters and Glycemic Levels in GDM Patients with Periodontitis. World J Dent 2022; 13 (4):320-327.

DOI: 10.5005/jp-journals-10015-2065

License: CC BY-NC 4.0

Published Online: 18-06-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim: To evaluate the effect of nonsurgical periodontal therapy on clinical periodontal parameters in pregnant periodontitis study participants with and without gestational diabetes mellitus (GDM) and to estimate the changes in glycemic level in GDM study participants with periodontitis, before and after periodontal therapy. Materials and methodology: The present study is an interventional, prospective trial. A total of 120 study participants were selected. Each subject was randomly assigned to one of the four groups comprising 30 study participants in each group, based on the diagnosis of the disease. Group 1 included pregnant study participants with GDM with periodontitis, group 2 included pregnant study participants with GDM with periodontitis, group 3 included pregnant study participants with periodontitis, and group 4 included pregnant study participants with periodontitis. Periodontal therapy comprising of scaling and root planing followed by oral hygiene instruction was performed in group 2 and group 4, whereas only oral hygiene instructions were given in group 1 and group 3 in the study participants at baseline. Periodontal parameters and glycemic levels were reassessed before parturition. The study data was analyzed using Statistical Package for Social Sciences (SPSS) software V.22, IBM, Corp. for Windows. Results: The study showed a significant reduction in all the clinical parameters in both the groups following nonsurgical periodontal therapy, along with a reduction in glycemic levels. However, the results were better in group 2 as compared to all other groups. Conclusion: Nonsurgical periodontal therapy (NSPT) in pregnant periodontitis study participants with or without GDM showed better clinical results and a reduction in glycemic levels. Clinical significance: Improvement in periodontal clinical parameters and reduction in glycemic levels following nonsurgical periodontal therapy in GDM with periodontitis study participants.


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  1. Preshaw PM, Alba AL, Herrera D, et al. Periodontitis and diabetes: a two-way relationship. Diabetologia 2012;55(1):21–31. DOI: 10.1007/s00125-011-2342-y
  2. Michalowicz BS, Hodges JS, Novak MJ, et al. Change in periodontitis during pregnancy and the risk of pre-term birth and low birthweight. J Clin Periodontol 2009;36(4):308–314.
  3. Bobetsis YA, Barros SP, Offenbacher S. Exploring the relationship between periodontal disease and pregnancy complications. J Am Dent Assoc 2006;137Suppl:7S–13S. DOI: 10.14219/jada.archive.2006.0403
  4. Carpenter MW. Gestational diabetes, pregnancy hypertension, and late vascular disease. Diabetes care 2007;30(Suppl 2):S246–S250. DOI:10.2337/dc07-s224
  5. Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963;21(6):533–551. DOI: 10.3109/00016356309011240
  6. Silness J, Löe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta odontologica scandinavica. Acta Odontol Scand 1964;22(1):121–135. DOI: 10.3109/00016356408993968
  7. Mealey BL, Ocampo GL. Diabetes mellitus and periodontal disease. J Periodontol 2006;77(8):1289-1303. DOI: 10.1902/jop.2006.050459
  8. Grant–Theule DA. Periodontal disease, diabetes, and immune response: a review of current concepts. J West Soc Periodontol Periodontal Abstr 1996;44(3):69-77. PMID: 9477864.
  9. Tarannum F, Faizuddin M. Effect of periodontal therapy on pregnancy outcome in women affected by periodontitis. J Periodontol 2007;78(11):2095–103. DOI: 10.1902/jop.2007.060388
  10. Tarannum F, Prasad S, Vivekananda L, et al. Awareness of the association between periodontal disease and pre-term births among general dentists, general medical practitioners and gynecologists. Indian J Public Health 2013;57(2):92–95. DOI: 10.4103/0019-557x.114992
  11. Offenbacher S, Boggess KA, Murtha AP, et al. Progressive periodontal disease and risk of very preterm delivery. Obstet Gynecol 2006;107(1):29–36. DOI: 10.1097/01.AOG.0000190212.87012.96
  12. Engebretson SP, Hyman LG, Michalowicz BS, et al. The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: a randomized clinical trial. Jama 2013;310(23):2523–2532. DOI: 10.1001/jama.2013.282431
  13. Joseph R, Sasikumar M, Mammen J, et al. Nonsurgical periodontal-therapy improves glycosylated hemoglobin levels in pre-diabetic patients with chronic periodontitis. World J Diabetes 2017;8(5):213–221. DOI: 10.4239/wjd.v8.i5.213
  14. Esteves Lima RP, Miranda Cota LO, Costa FO. Association between periodontitis and gestational diabetes mellitus: a case-control study. J Periodontol 2013;84(9):1257–1265. DOI: 10.1902/jop.2012.120350
  15. Elkadi OM, Madkour GG, Elmenoufy HS, et al. Evaluation of level of TNF-α in chronic periodontitis patients with gestational diabetes mellitus after phase I periodontal therapy. Dent J 2018;9(3):555763. DOI: 10.19080/ADOH.2018.09.555763
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