Comparative Clinical Evaluation of Two Local Drug Delivery Agents (Neem Chip and Turmeric Chip) in Chronic Periodontitis: An Experimental Study
Komal Saini, Priyanka Chopra, Amit Bhardwaj, Manish Yadav, Sachin Saini
Chronic periodontitis, Curcumin, Local drug delivery, Neem chip, Turmeric chip
Citation Information :
Saini K, Chopra P, Bhardwaj A, Yadav M, Saini S. Comparative Clinical Evaluation of Two Local Drug Delivery Agents (Neem Chip and Turmeric Chip) in Chronic Periodontitis: An Experimental Study. World J Dent 2021; 12 (2):138-143.
Aim and objective: This study aimed to evaluate the efficacy of herbal local drug delivery (LDD) agents as an adjunct to scaling and root planing (SRP) and SRP alone in the treatment of chronic periodontitis.
Material and methods: This split-mouth study was conducted at the Department of Periodontology, SGT Dental College, Haryana, in 30 patients between 30 years and 65 years of age where 90 sites (3 sites in one patient) were selected. Only those teeth with probing pocket depth (PPD) of ≥5 mm were included. Sites were randomized into three treatment groups. Group I with SRP + neem chip, group II with SRP + turmeric chip, and group III received SRP only. Clinical parameters plaque index (PI), gingival index (GI), PPD, and relative attachment level (RAL) were recorded at baseline, 1 month after the intervention, and at 3 months. Intergroup comparisons were done using Kruskal–Wallis test followed by post hoc comparison using Mann–Whitney U test.
Results: Mean PI and GI at 1 month for group I, II, and III were (1.33 ± 0.28, 1.37 ± 0.28, and 1.66 ± 0.27) (1.20 ± 0.31, 1.24 ± 0.26, and 1.31 ± 0.39), respectively. Improvement in mean PI and mean GI of group I and group II at 1 month is significant when compared with group III (p < 0.05). Probing pocket depth at 1 month for group I, II, and III was 4.16 ± 0.88, 4.21 ± 0.61, and 4.63 ± 0.68, respectively (p < 0.05 for all groups). Mean RAL at 1 month for group I, II, and III was 8.41 ± 1.59, 8.43 ± 1.66, and 9.01 ± 1.50, respectively. The mean RAL of group I and group II is significant when compared with group III at 1 month (p < 0.05).
Conclusion: Better immediate results can be achieved in the management of chronic periodontitis by the use of locally delivered neem and turmeric extract in form of chips.
Clinical significance: These herbal chips are natural, cost-effective without any side effects, and can be used in treating chronic periodontitis.
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