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VOLUME 11 , ISSUE 6 ( November-December, 2020 ) > List of Articles


Antiplaque and Antigingivitis Effectiveness of Tea Tree Oil and Chlorine Dioxide Mouthwashes among Young Adults: A Randomized Controlled Trial

Aarya N Bharadwaj, Vijayalakshmi Byatappa, Rekha Raju, Rekha Umakanth, Prajila Alayadan

Keywords : Dental plaque, Gingivitis, Mouthwashes, Oral hygiene, Tea tree oil,Chlorine dioxide

Citation Information : Bharadwaj AN, Byatappa V, Raju R, Umakanth R, Alayadan P. Antiplaque and Antigingivitis Effectiveness of Tea Tree Oil and Chlorine Dioxide Mouthwashes among Young Adults: A Randomized Controlled Trial. World J Dent 2020; 11 (6):451-456.

DOI: 10.5005/jp-journals-10015-1765

License: CC BY-NC 4.0

Published Online: 03-04-2021

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Aim: Gingivitis is a common oral condition that can lead to severe dental complications. Prior research has shown the antimicrobial efficacies of tea tree oil (TTO) and chlorine dioxide (ClO2) against oral microorganisms. The aim of this study is to evaluate the effect of these mouthwashes against dental plaque accumulation and gingival inflammation among young adults. Materials and methods: This study followed a single-center, parallel-group, double-blind, randomized controlled trial design and was conducted in Bengaluru among 60 participants aged 18–25 years. Participants were randomly allocated into one of the three study groups (chlorhexidine, TTO, chlorine dioxide) with 20 participants in each and used the respective mouthwash twice daily along with other oral hygiene practices. The modified Silness and Loe plaque index and the Loe and Silness gingival index were used to assess plaque accumulation and gingival inflammation at both times—baseline and follow-up (21 days). The paired t-test and nonparametric tests like Wilcoxon sign-rank test and Kruskal–Wallis test with post hoc Dunn test were used to assess the outcome measures. A p value of <0.05 was considered statistically significant. Results: A statistically significant reduction in mean gingival and plaque scores was observed in all three groups after 21 days. Tea tree oil and chlorhexidine were comparable in reducing plaque scores, whereas chlorhexidine was superior in reducing gingival scores. Conclusion: Tea tree oil and chlorine dioxide were effective in reducing plaque accumulation and gingivitis and could be suitable alternatives for chlorhexidine. Clinical significance: Mouthwashes are the most widely used chemical adjuncts to mechanical plaque control and adverse effects of chlorhexidine digluconate have limited its use in cases of gingivitis. Thus, among the alternatives available, there is a need for the product with minimum side effects and maximum efficacy and so this study evaluated the effect of TTO and chlorine dioxide mouth rinses and compared their effects with chlorhexidine against dental plaque accumulation and gingival inflammation among young adults.

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