World Journal of Dentistry

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VOLUME 11 , ISSUE 2 ( March-April, 2020 ) > List of Articles


Suture Granuloma in Oral Biopsy Specimen

Gargi S Sarode, Namrata Sengupta, Yaser A Alhazmi

Keywords : Foreign body reaction, Histopathology, Oral pathology, Suture granuloma

Citation Information : Sarode GS, Sengupta N, Alhazmi YA. Suture Granuloma in Oral Biopsy Specimen. World J Dent 2020; 11 (2):161-163.

DOI: 10.5005/jp-journals-10015-1719

License: CC BY-NC 4.0

Published Online: 18-07-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Aim: To give perspective on suture granuloma in oral biopsy specimens. Background: Suture granuloma is an uncommon finding in the oral biopsy specimens. Suture granulomas may give the impression of both benign and malignant lesions, thus posing a serious diagnostic challenge. Hence, it is very important that oral pathologists should understand pathogenesis and histopathology of this rare phenomenon. Results: Suture granuloma evokes immunological reaction with recruitment of monocyte macrophages, which ultimately forms epithelioid cells and giant cells. The pathogenetic events were driven by the factors such as interleukins, MHC class II molecules, CD4+ Th1 lymphocytes, transforming and platelet derived growth factors. Histopathologically, they are easy to identify due to characteristic appearance of granuloma surrounding the suture material. Conclusion: This paper presents a very rare occurrence of suture granuloma in an oral biopsy specimen with special emphasis on pathogenesis and histopathology. Clinical relevance: Accidental findings in oral pathologies are not very common evidence. Suture granuloma is one such phenomenon that can be mistaken for benign or malignant neoplasm. Hence, it becomes of paramount importance to realize the need of understanding this phenomenon for oral pathologists to avoid diagnostic confusion. This short communication elaborates the histomorphological appearance of suture granuloma, which will help pathologists in accurate diagnosis and hence management.

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