Aim: This review provides an overview of various classifications and aims to focus on the characteristic distinguishing features of oral verrucopapillary lesions that direct towards arriving at a diagnosis and assessment of their biologic behavior.
Background: A variety of pathological conditions affect the normal morphologic and surface characteristics of the oral mucosa. Verrucopapillary lesions (VPLs) are one such group of diseases that are diagnostically disputed and comprise of a spectrum of reactive, benign and malignant lesions. They can be categorized broadly into focal and multifocal lesions.
Review results: The classic clinical, histopathological and Immunohistochemical characteristics of oral verrucopapillary lesions may help in their accurate diagnosis.
Clinical significance: Despite, few indistinguishable clinical presentations of VPLs, their specific morphology, etiology, and discrete histopathological features may ease out the diagnostic dilemma and facilitate appropriate treatment.
Vala D, Maiti SB, Ranjan R, et al. Verrucous papillary lesions of oral mucosa-a review. Journal of Advanced Medical and Dental Sciences Research. 2016;4(6):52-67.
Kapoor C, Dhanpal R, Shetty C, et al. Verruco-papillary lesions in relation to human papilloma virus. Journal of cancer research and therapeutics 2013;9(3):541-542.
Thomas GJ, Barrett AW. Papillary and verrucous lesions of the oral mucosa. Diagnostic Histopathology 2009;15(6):279-285.
Regezi JA, Sciubba JJ, Jordan RC. Oral pathology: clinical pathologic correlations. 6th ed. Elsevier Health Sciences 2016 Feb 25.
Neville BW, Damm DD, Chi AC, et al. Oral and maxillofacial pathology.3rd ed. Elsevier Health Sciences; 2015.
Jaju PP, Suvarna PV, Desai RS. Squamous papilloma: case report and review of literature. International Journal of Oral Science 2010;2(4):222-225.
Hegde U, Doddawad VG, Sreeshyla HS, et al. Verruciform xanthoma: A view on the concepts of its etiopathogenesis. Journal of oral and maxillofacial pathology: JOMFP 2013;17(3):392-396.
Ural A, Arslan S, Ersöz Ş, et al. Verruca vulgaris of the tongue: a case report with literature review. Bosnian Journal of Basic Medical Sciences 2014;14(3):136-138.
Mehrotra D, Goel M, Kumar S, et al. Oral verrucous lesions: Controversies in diagnosis and management. Journal of Oral Biology and Craniofacial Research 2012;2(3):163-169.
Santoro A, Pannone G, Contaldo M, et al. A troubling diagnosis of verrucous squamous cell carcinoma (“the bad kind” of keratosis) and the need of clinical and pathological correlations: a review of the literature with a case report. Journal of Skin Cancer 2011;2011.
Lambson GO. Papillary hyperplasia of the palate. The Journal of Prosthetic Dentistry 1966;16(4):636-645.
Kwiek B, Schwartz RA. Keratoacanthoma (KA): An update and review. Journal of the American Academy of Dermatology. 2016 Jun 1;74(6): 1220-1233.
Zain RB, Kallarakkal TG, Ramanathan A, Kim J, Tilakaratne WM, Takata T, Warnakulasuriya S, Hazarey VK, Rich A, Hussaini HM, Jalil A. Exophytic Verrucous Hyperplasia of the Oral Cavity– Application of Standardized Criteria for Diagnosis from a Consensus Report. Asian Pacific Journal of Cancer Prevention 2016;17(9): 4491-4501.
Fitzpatrick SG, Neuman AN, Cohen DM, et al. Papillary variant of squamous cell carcinoma arising on the gingiva: 61 cases reported from within a larger series of gingival squamous cell carcinoma. Head and Neck Pathology 2013;7(4):320-326.
Fooanant S, Pattarasakulchai T, Tananuvat R, et al. Sinonasal papilloma in chiangmai university hospital. J Med Assoc Thai 2013;96(3):329-333.