World Journal of Dentistry

Register      Login

VOLUME 7 , ISSUE 4 ( October-December, 2016 ) > List of Articles

RESEARCH ARTICLE

Effect of Air Pollution on Salivary Interleukin-8 Levels in Children

Solmaz Pourzare Mehrbani, Zohreh Babaloo, Zahra Jamali, Tahmoores Abdollahian, Hosein Eslami, Narges Sobhani

Citation Information : Mehrbani SP, Babaloo Z, Jamali Z, Abdollahian T, Eslami H, Sobhani N. Effect of Air Pollution on Salivary Interleukin-8 Levels in Children. World J Dent 2016; 7 (4):175-178.

DOI: 10.5005/jp-journals-10015-1390

Published Online: 01-12-2016

Copyright Statement:  Copyright © 2016; The Author(s).


Abstract

Background

Air pollution in cities has always been a permanent and serious threat for the health of society and the environment, influencing the health of different body organs and systems both acutely and chronically. Therefore, the aim of this study is to investigate the effect of air pollution in saliva Interleukin-8 (IL-8) levels in children.

Materials and methods

A total of 88, 8- to 10-year-old children were included in this descriptive cross-sectional study. Group I, the case group, included 44 children from Tabriz (Iranian Azerbaijan), and group II, the control group, included 44 children from Kalibar Town (of Tabriz). Both groups in this study had a similar economic status. Following sampling and selection of individuals, for measuring the levels of saliva IL-8, ELISA (enzyme-linked immunosorbent assay) method was used. To investigate the difference between the means of the groups, independent t test or its nonparametric equivalent, i.e., Man—Whitney test and Statistical Package for the Social Sciences (SPSS) 21 were used. In this study, p-value lower than 0.05 was considered statistically significant.

Results

The results of this study indicate a significant difference in the levels of saliva IL-8 between the two groups, where the mean level of saliva IL-8 is greater in children residing in the region with higher air pollution level than in the children dwelling in the region with a greater air pollution level (p = 0.001).

Conclusion

The results obtained from this study indicated that the level of saliva IL-8 increases in regions with air pollution, potentially causing several mouth problems in children.

How to cite this article

Mehrbani SP, Babaloo Z, Jamali Z, Abdollahian T, Eslami H, Sobhani N. Effect of Air Pollution on Salivary Interleukin-8 Levels in Children. World J Dent 2016;7(4):175-178.


PDF Share
  1. Study of particulate air pollution Gachsaran in 2005. J Armaghan Danesh 2007;12(2):89-97.
  2. Study of air pollution effect on human's health in 2012. Available from: http://www.civilica.com/Paper-SDCONF01-SDCONF01_1951.html
  3. Public health impact of outdoor and trafficrelated air pollution: a European assessment. Lancet 2000 Sep;356(9232):795-801.
  4. Air pollution as an emerging global risk factor for stroke. JAMA 2011 Mar;305(12):1240-1241.
  5. Association of allergic asthma emergency room visits with the main biological and chemical air pollutants. Sci Total Environ 2012 Aug;432:288-296.
  6. Health effects of air pollution. J Allergy Clin Immunol 2004 Nov;114(5):1116-1123.
  7. Concentrations of lead in blood, hair and saliva of German children living in three different areas of traffic density. Sci Total Environ 2002 Oct;297(1-3):109.
  8. Human cytokines. 3rd ed. Philadelphia: Saunders Co; 2004:p. 36-41.
  9. Enhanced interleukin-8 secretion in circulation of patients with Behcets disease. J Rheumatol 1995;22(5):904-907.
  10. Human neutrophil activating peptide/interleukin-8 acts as an autoantigen in rheumatoid arthritis. Ann Rhenum Dis 1992 Jan;51(1):19-22.
  11. National Environment Agency of Singapore. Retrieved 15 April 2014.
  12. Salivary composition and calculus formation in patients undergoing hemodialysis. J Periodontol 1980 Jun;51(6):336-338.
  13. Air pollution, oxidative stress and dietary supplementation: a review. Eur Respir J 2008 Jan;31(1):179-197.
  14. Copper-dependent inflammation and nuclear factor-ê B activation by particulate air pollution. Am J Respir Cell Mol Biol 1998 Sep;19(3):366-378.
  15. The effects of outdoor air pollution and tobacco smoke on asthma. Immunol Allergy Clin North Am 2005 Feb;25(1):15-30.
  16. Traffic-related air pollution affects peak expiratory flow, exhaled nitric oxide, and inflammatory nasal markers. Arch Environ Health 2001 Mar-APr;56(2):167-174.
  17. Indoor air pollutants stimulate interleukin-8-specific Mrna expression and protein secretion of alveolar macrophages. Lung 1999;177(1):9-19.
  18. Comparison of serum interleukin-8 levels in patients with recurrent aphthous stomatitis and healthy individuals. J Islamic Dent Assoc Iran 2007;19(1):78-82.
  19. Evaluation of serum levels of interleukin-6 and -8 in patients with recurrent aphthous ulcerations. J Dent 2009;9(4):21-26.
  20. Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children. Environ Health Perspectives 2009 Apr;117(4):668-674.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.