When the Unthinkable Happens: Universal Work Precautions and Postexposure Prophylaxis in HIV
Praveen Ramdurg, Sharanappa Kambale, Vijaylaxmi B Mendigeri, Mohammad Fayyaz
Citation Information :
Ramdurg P, Kambale S, Mendigeri VB, Fayyaz M. When the Unthinkable Happens: Universal Work Precautions and Postexposure Prophylaxis in HIV. World J Dent 2011; 2 (4):332-337.
Postexposure prophylaxis (PEP) with antiretrovirals is now widely used worldwide after either occupational contact (with blood or another blood-containing fluid), or nonoccupational contact (mainly sexual or injection-drug use). It is assumed to reduce the risk of HIV transmission by at least 80%, although its efficacy has not been completely proven. Several countries have issued guidelines to help the clinician in their decision to offer PEP and to improve its cost-effectiveness. This article reviews the different antiretroviral combinations used, their safety profile, the recommendations and indications of PEP.
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