Citation Information :
Vemareddy R, Naidu S, Korrai BR, Nagadevara S, Battu S, Thati J, Kavuri S. Evaluating the Efficacy of Titanium Dioxide Nanoparticles in Combination with Commonly Used Bleaching Agents: An In Vitro Study. World J Dent 2024; 15 (5):377-380.
Aim: To evaluate the efficacy of titanium dioxide (TiO2) nanoparticles in combination with hydrogen peroxide (H2O2) and carbamide peroxide (CH6N2O3).
Materials and methods: A total of 40 freshly extracted maxillary central incisors were discolored by storing them in a freshly prepared coffee solution for 2 weeks and subjected to spectroscopic analysis. Baseline values L1, a1, and b1 of each sample were recorded. The teeth were then randomly divided into four groups (n = 10)—group I was treated with 35% H2O2; group II was treated with TiO2 nanoparticles and 15% H2O2; group III was treated with 15% CH6N2O3; and group IV was treated with TiO2 nanoparticles and 15% CH6N2O3. Immediately after treatment, the samples were analyzed spectroscopically, and the L2, a2, and b2 values of each sample were recorded. The samples were then stored in artificial saliva solution for 7 days and analyzed spectroscopically again, recording L3, a3, and b3 values of each sample. The difference was measured as ΔE*2-1 and ΔE*3-2 for each sample, and the data recorded was statistically analyzed.
Results: Mean change in color difference (ΔE*2-1) was higher in group II (2.8200 ± 0.74294) than in group I (2.4300 ± 0.50594) and group IV (2.1360 ± 0.56400) than in group III (2.0910 ± 0.58711). Group II had the highest mean, followed by groups I, IV, and III, respectively. The mean change in color difference (ΔE*3-2) was higher in group II (7.3820 ± 1.31952) than in group I (5.7550 ± 1.18895) and group IV (4.3800 ± 1.56449) than in group III (4.1140 ± 1.00087). Group II had the highest mean, followed by groups I, IV, and III, respectively. The results obtained were statistically significant.
Conclusion: The use of TiO2 nanoparticles with lower concentrations of H2O2 and CH6N2O3 has increased the efficiency and longevity of the traditional bleaching agent.
Clinical significance: Around 35% of H2O2 is a commonly used bleaching agent, but according to some studies, higher concentrations of H2O2 cause sensitivity in patients. Decreasing the concentration of H2O2 helps decrease the postoperative sensitivity. The addition of nano-TiO2, even with less concentration, gains high efficiency as a bleaching material.
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