Aim: To assess soft tissue (ST) responses to camouflage orthodontic treatment in patients with class II skeletal patterns. Materials and methods: Based on the inclusion and exclusion criteria, pre- and posttreatment cephalometric radiographs of 37 young adult patients were imported, digitized, and superimposed. The posttreatment values were inserted in the “Goals” tab of the “Treatment Simulation” section of the Dolphin imaging software. The Dolphin imaging software predicted a posttreatment cephalogram. The Dolphin measurement function was used to record the values of ST changes from the actual posttreatment and the predicted treatment outcomes. The discrepancies in ST changes between predicted and actual values were calculated. Results: Soft tissue (ST) subnasale to H-line, upper lip strain (ULS), and inferior sulcus (IS) to H-line (IS–H-line) showed statistically significant differences from the actual changes. The prediction of all the parameters except for ULS and IS to H-line was underestimated. Conclusion: This study showed that the most accurate prediction was found in nose prominence (NP) and superior sulcus depth (SSD), and the most inaccurate prediction was found in ST subnasale to the H-line. Therefore, with caution, Dolphin imaging software can be used for ST prediction and patient education. Clinical significance: Treatment forecast is crucial and beneficial in borderline and camouflage cases to predict the posttreatment changes to the face and develop alternate treatment plans, especially in patients with esthetic concerns.