Osteogenic Potential of Tooth as Autogenous Bone Graft in Dental Extraction Sites: A Split-mouth Randomized controlled Human Trial
Satya Prakash, Dhanraj Ganapathy, Padma Ariga, Ashok K Sundramoorthy
Keywords :
Autogenous bone grafting, Grinder, Implants, Teeth
Citation Information :
Prakash S, Ganapathy D, Ariga P, Sundramoorthy AK. Osteogenic Potential of Tooth as Autogenous Bone Graft in Dental Extraction Sites: A Split-mouth Randomized controlled Human Trial. World J Dent 2023; 14 (1):52-61.
Aim: The aim of the study was to evaluate the osteogenic potential of autologous tooth graft used in dental extraction sites.
Materials and methods: This study was an in vivo, split-mouth, and randomized control trial comparing the effectiveness of autologous tooth grafts in bone formation. A total of 11 patients undergoing bilateral extractions of the analogous teeth were selected after obtaining informed consent and ethical clearance. The atraumatic extraction site allowed to heal normally served as the control (group I) and the extraction site grafted with tooth autologous material served as the intervention (group II). The outcome measures were postoperative pain, discomfort, and qualitative and quantitative bone formation assessed by histological and tomographic methods.
Results: The mean total bone formation assessed histomorphometrically was 4.45 ± 2.77 and 21.69 ± 14.6 parts per hundred (PPH) for groups I and II, respectively. The mean total bone formation assessed using the tomographic scale was 0.63 ± 0.48 and 3.27 ± 0.44 for groups I and II, respectively. Statistically significant bone formation was observed in the intervention group (p < 0.01).
Conclusion: Tooth as an autologous bone graft can be a viable option for grafting in regions of inadequate bone which is substantiated by the results of this study.
Clinical significance: The autologous tooth graft obtained demonstrated excellent osteogenic potential in dental extraction sites, as revealed by definitive histomorphometric and imaging evidence. This can be used as an effective, economical, and potent graft material in conditions requiring osseous repair and reconstruction.
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