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VOLUME 14 , ISSUE 1 ( January, 2023 ) > List of Articles

ORIGINAL RESEARCH

In Vitro Evaluation of Incorporation of Zirconium Oxide Nanoparticle and Antibiotics on the Physical Properties of Glass Ionomer Cement

Priyanka Venugopal, Parvathy Kumaran, Balagopal R Varma, Suresh Kumar Janardhanan, Arun M Xavier

Keywords : Antibiotics, Compressive strength, Fluoride release, Glass ionomer cement, Zirconium oxide nanoparticles

Citation Information : Venugopal P, Kumaran P, Varma BR, Janardhanan SK, Xavier AM. In Vitro Evaluation of Incorporation of Zirconium Oxide Nanoparticle and Antibiotics on the Physical Properties of Glass Ionomer Cement. World J Dent 2023; 14 (1):21-26.

DOI: 10.5005/jp-journals-10015-2159

License: CC BY-NC 4.0

Published Online: 27-03-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Aims and objectives: To evaluate and compare the compressive strength and fluoride release of conventional glass ionomer cement (GIC) with zirconium oxide (ZrO2) nanoparticle and antibiotic-enriched glass ionomer cement. Materials and methods: A total of 30 specimens in three groups comprising group I (control): Fuji IX GIC, group II A: 3% ZrO2 nanoparticles + GIC, group II B: 1.5% ZrO2 nanoparticles + GIC, group III A: 3% (ciprofloxacin + cefuroxime = 1:1) + GIC, and group III B: 1.5% (ciprofloxacin + cefuroxime = 1:1) + GIC were prepared in a transparent polyethylene tubing of 10 × 4 mm dimension. All the prepared specimens were stored in distilled water (37°C) for 24 hours. Compressive strength and fluoride release were evaluated using the universal testing machine (UTM) and Orion 940 ion analyzer, respectively. Then the values were compared. To test the statistical significance of the comparison of compressive strength and fluoride release between the groups, the Kruskal–Wallis test and Bonferroni multiple-comparison tests were used. Results: The mean compressive strength was observed to be highest with group II A (94.13 MPa ± 1.81) and least with group III A (62.80 MPa ± 1.53). The highest and lowest mean fluoride releases after 24 hours were observed in group II A (18.40 ppm ± 1.32) and group I (10.10 ± 0.36), respectively. However, the difference in the amount of fluoride released from group II A was not statistically significant at the end of 7 days. Conclusion: Zirconium oxide enriched GIC (3% w/w) has added fluoride release and compressive strength than antibiotic enriched GIC and conventional GIC. Clinical significance: Modifications of GIC have substantially improved the physio-mechanical properties. The application of ZrO2 nanoparticles significantly increased the compressive strength and fluoride release of GIC.

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