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VOLUME 13 , ISSUE S1 ( Supplementary Issue 1, 2022 ) > List of Articles


Comparative Evaluation of the Efficacy of Pro-Argin-containing Desensitizing Toothpaste vs Mouthwash: An In Vitro Study

Arunav Gogoi, Parichaya Batra, C Preeja, KJ Nisha

Keywords : Dentin desensitizing agents, Dentin hypersensitivity, Mouthwashes

Citation Information :

DOI: 10.5005/jp-journals-10015-2120

License: CC BY-NC 4.0

Published Online: 01-10-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Aim: The aim of this study was to evaluate if Pro-Argin mouthwash is as efficient as Pro-Argin paste at occluding dentinal tubules and reducing dentin hypersensitivity (DH). Materials and methods: The study used 90 dentin disks that were free of enamel and pulp horns. They were divided into three groups of 30 disks each at random: group I: saline-immersed dentin disks, group II: paste-immersed dentin disks, and group III: mouthwash-immersed dentin disks. On the 1st, 15th, and 30th days, specimens from three groups underwent scanning electron microscopic analysis. Results: The lower the occlusion score, the fewer the open dentinal tubules and the better the tubule occlusion. The mean intergroup occlusion scores for the paste and mouthwash groups on days 1, 15, and 30 showed significantly higher dentinal tubule occlusion than the saline group at p < 0.001. The intragroup comparison of mean dentinal tubule occlusion scores on days 1, 15, and 30 using the repeated measures analysis of variance (ANOVA) test revealed no significant differences between time intervals in each study group. Conclusion: The study found that using Pro-Argin mouthwash to occlude dentinal tubules can be a viable option for reducing hypersensitivity. Clinical significance: When translated into clinical practice, this finding can be especially beneficial to patients recovering from periodontal surgery, where brushing with a paste is not recommended in the first postoperative week.

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