World Journal of Dentistry

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VOLUME 13 , ISSUE 4 ( July-August, 2022 ) > List of Articles


An Unusual Case of Intravascular Oral Nodular Fasciitis: A Case Report/Review

Wafa Khan, Vanishri Haragannavar, Anand Devaraj, BR Rajanikanth, Kavitha Prasad, Roopa S Rao, SV Sowmya, Dominic Augustine, Shankargouda Patil

Keywords : Muscle specific actin, Nodular fasciitis, Smooth muscle actin, Vimentin

Citation Information : Khan W, Haragannavar V, Devaraj A, Rajanikanth B, Prasad K, Rao RS, Sowmya S, Augustine D, Patil S. An Unusual Case of Intravascular Oral Nodular Fasciitis: A Case Report/Review. World J Dent 2022; 13 (4):412-416.

DOI: 10.5005/jp-journals-10015-2074

License: CC BY-NC 4.0

Published Online: 18-06-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Aim: The term spindle cell lesion, or tumor, is a purely descriptive one. This manuscript aims to report a rare case of nodular fasciitis (NF). Background: Nodular fasciitis is a rapidly growing soft tissue myofibroblastic lesion that represents a tumor-like mass with low recurrence rate of 1–2%. Upto 20% of cases are reported to occur in the head and neck region but these lesions in the oral cavity are extremely rare and tend to affect children more. Case report: Overlapping clinico-radiographic and microscopic features make NF a diagnostic challenge not only for the clinicians but for the histopathologist as well. The case reported here is unique because of its occurrence in older age-group and its location. Conclusion: The deceptive clinical behavior coupled with nonspecific histologic features makes this lesion challenging to diagnose. Accurate diagnosis is important to avoid unnecessary and mutilating surgeries. Clinical significance: Immunohistochemistry (IHC) panel of markers vimentin, smooth muscle actin, muscle specific actin, desmin, CD34, S-100, and Ki-67 aided in solving the diagnostic dilemma.

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