Aim and objective: This study aimed to investigate the retention and bite force in completely edentulous patients with torus palatinus rehabilitated with two designs, one with window to accommodate the tori which is later modified to a horseshoe-shaped complete denture. Materials and methods: A total of 66 patients, with tori requiring complete denture, were included in the study. The retention was measured during 3 months follow-up with both designs. The denture bases with different designs were subjected for evaluation of retention using a Handheld Digital Push-Pull Force Gauge Meter to evaluate the retentive values of the denture bases. The bite force was measured at the first molar region by a custom-built occlusal force meter at 1 week, 1 month and 3 months intervals during follow-up. Results: The results of the study showed that there was not much significant difference between the two denture designs in terms of their retention. The mean biting force was statistically significant different between both the designs, with the horseshoe design showing higher values compared to the denture with window. Conclusion: Among the two designs, retention values were approximately the same with both the designs and there was a significant difference in bite force values with the horseshoe-shaped denture. Clinical significance: Some intraoral anatomical features can negatively affect certain patients and complicate prosthodontic intervention. In this study, the horse shoe-shaped complete denture proved to be an effective treatment option compared to the denture with the window.