World Journal of Dentistry

Register      Login

VOLUME 13 , ISSUE 2 ( March-April, 2022 ) > List of Articles


Clinical Evaluation of an Essential Oil Intraoral Spray for Treatment of Dry Mouth

Vaishali Balyan, S Mahantesha, Vedika Talwar, Sugandha Mishra, Sneha Joseph

Keywords : Desensitization, Essential oil, Propolis, Xerostomia

Citation Information : Balyan V, Mahantesha S, Talwar V, Mishra S, Joseph S. Clinical Evaluation of an Essential Oil Intraoral Spray for Treatment of Dry Mouth. World J Dent 2022; 13 (2):110-115.

DOI: 10.5005/jp-journals-10015-1916

License: CC BY-NC 4.0

Published Online: 31-01-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Aim: To assess the effect of essential oil intraoral spray for dry mouth. Composition of spray: essential oil (peppermint oil 1 mL), propolis (1.5 mL), xylitol (700 mg), ethyl alcohol (10 mL), and water (up to 50 mL). Materials and methods: A total of 30 patients with dry mouth symptoms were selected for the study (study group). Clinical parameters such as gingival index, plaque index, and visual analog scale (VAS) for xerostomia and desensitization were recorded. A total of 30 patients were selected for control group. Two intraoral sprays were formulated one for each group. The results of both groups were then analyzed. Results: Statistical difference was obtained in the various parameters between the two groups. Mean gingival index (GI) score in control group at baseline was found to be 0.489 + 1.242 and postoperative it was 0.271 + 0.109. There was a statistically significant difference in mean GI score between baseline and postoperative at 5% significance level (p = 0.001). Mean salivary rate (SR) score in control group at baseline was found to be 2.400 + 1.242 and postoperative it was 2.066 + 0.961. There was no statistically significant difference in mean SR score between baseline and postoperative at 5% significance level (p = 0.298). Conclusion: Essential oil and propolis spray are effective in improving oral health of patients suffering from dry mouth and dentinal hypersensitivity. It also ensured better patient compliance. Hence, encouraged them to use as prescribed. Clinical significance: Essential oil intraoral spray has all the advantages of promoting oral health by treating xerostomia, dentinal hypersensitivity, and less plaque accumulation; thus, improving the overall health.

  1. Sbordone L, Bortolaia C. Oral microbial biofilms and plaque-related diseases: microbial communities and their role in the shift from oral health to disease. Clin Oral Investig 2003;7(4):181–188. DOI: 10.1007/s00784-003-0236-1
  2. Vlachojannis C, Chrubasik-Hausmann S, Hellwig E, et al. A preliminary investigation on the antimicrobial activity of Listerine®, its components, and of mixtures thereof. Phytother Res 2015;29(10):1590–1594. DOI: 10.1002/ptr.5399
  3. Charles CH, Sharma NC, Galustians HJ, et al. Comparative efficacy of an antiseptic mouthrinse and an antiplaque/antigingivitis dentifrice: a six-month clinical trial. J Am Dent Assoc 2001;132(5):670–675. DOI: 10.14219/jada.archive.2001.0245
  4. Fine DH. Mouthrinses as adjuncts for plaque and gingivitis management. A status report for the American Journal of Dentistry. Am J Dent 1988;1(6):259–263.
  5. Barnett ML. The role of therapeutic antimicrobial mouthrinses in clinical practice: control of supragingival plaque and gingivitis. J Am Dent Assoc 2003;134(6):699–704. DOI: 10.14219/jada.archive.2003.0255
  6. Bakhtiari S, Azimi HS, Esfandiari F, et al. Comparison of the effect of sugarfree orbit chewing gum & natural turpentine on salivary flow rate & pH.
  7. Marchetti E, Mummolo S, Di Mattia J, et al. Efficacy of essential oil mouthwash with and without alcohol: a 3-day plaque accumulation model. Trials 2011;12(1):1–7. DOI: 10.1186/1745-6215-12-262
  8. Purra AR, Mushtaq M, Acharya SR, et al. A comparative evaluation of propolis and 5.0% potassium nitrate as a dentine desensitizer: a clinical study. J Indian Soc Periodontol 2014;18(4):466. DOI: 10.4103/0972-124X.138695
  9. Atashi V, Yazdannik A, Mahjobipoor H, et al. The effects of Aloe vera-Peppermint (Veramin) moisturizing gel on mouth dryness and oral health among patients hospitalized in intensive care units: a triple-blind randomized placebo-controlled trial. J Res Pharm Pract 2018;7(2):104. DOI: 10.4103/jrpp.JRPP_18_21
  10. Plemons JM, Al-Hashimi I, Marek CL. Managing xerostomia and salivary gland hypofunction: executive summary of a report from the American Dental Association Council on Scientific Affairs. J Am Dent Assoc 2014;145(8):867–873. DOI: 10.14219/jada.2014.44
  11. Sivapathasundharam B. Shafer's Textbook of Oral Pathology-E Book. Elsevier Health Sciences 2016.
  12. Neville BW, Damm DD, Allen CM, et al. Oral and maxillofacial pathology. Elsevier Health Sciences 2015.
  13. Hu J, Andablo-Reyes E, Mighell A, et al. Dry mouth diagnosis and saliva substitutes: a review from a textural perspective. J Texture Stud 2021;52(2):141–156. DOI: 10.13039/100010663
  14. Guggenheimer J, Moore PA. Xerostomia: etiology, recognition and treatment. J Am Dent Ass 2003;134(1):61–69. DOI: 10.14219/jada.archive.2003.0018
  15. Fischman SL, Aguirre A, Charles CH. Use of essential oil-containing mouthrinses by xerostomic individuals: determination of potential for oral mucosal irritation. Am J Dent 2004;17(1):23–26.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.