World Journal of Dentistry

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VOLUME 11 , ISSUE 5 ( September-October, 2020 ) > List of Articles


Odontogenic Myxoma with Displaced Third Molar to Coronoid Process: Role of Differential Stains to Assess Biologic Behavior

Vineeth Kumar, Kavitha Prasad

Keywords : Alcian blue, Cone-beam computed tomography, Odontogenic myxoma, Picrosirius red, Polarizing microscope, SafraninO, Tooth displacement

Citation Information : Kumar V, Prasad K. Odontogenic Myxoma with Displaced Third Molar to Coronoid Process: Role of Differential Stains to Assess Biologic Behavior. World J Dent 2020; 11 (5):431-435.

DOI: 10.5005/jp-journals-10015-1739

License: CC BY-NC 4.0

Published Online: 14-12-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Aim: The aim of this case report is to document an aggressive odontogenic myxoma (OM) of the mandible causing dramatic displacement of the unerupted third molar up to the coronoid process, a rare entity. Background: The OM is an aggressive neoplasm that can cause significant destruction of the jaws. They present as large multilocular lesions often causing thinning of the cortical plates and displacement of teeth. The OM has a high rate of recurrence that brings into significance their mode of management that varies from curettage to radical excision depending on the surgeon\'s school of thought. Case description: An OM of the mandible in a 17-year-old patient is described here with cone-beam computed tomography (CBCT) and orthopantomograph (OPG) findings. The OM had displaced the unerupted mandibular third molar to the coronoid process that makes this case interesting to report. Conclusion: Intensity of alcian blue and safranin O staining reveal the hyaluronic acid, glycosaminoglycans (GAG\'s), and proteoglycan content of OM. The pattern of picrosirius red staining under polarizing microscope indicates aggressive potential of OM. Clinical significance: The article highlights the use of appropriate differential stains like alcian blue, safranin O, and picrosirius red that facilitate in arriving at precise biologic behavior of OM. Original research studies to validate intensity and pattern of special stains with odontogenic lesions are mandated to establish a significant correlation.

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