World Journal of Dentistry

Register      Login

VOLUME 10 , ISSUE 5 ( September-October, 2019 ) > List of Articles

ORIGINAL RESEARCH

Patterns of Tobacco Consumption among Oral Squamous Cell Carcinoma Cases Attending a Tertiary Care Dental Hospital in Coastal Karnataka of India

Shankaran V Sreelatha, Sukanya Shetty, Vimal K Karnaker, Chitta R Chowdhury

Keywords : Carcinoma, Habits, Smoke, Squamous cell, Tobacco

Citation Information : Sreelatha SV, Shetty S, Karnaker VK, Chowdhury CR. Patterns of Tobacco Consumption among Oral Squamous Cell Carcinoma Cases Attending a Tertiary Care Dental Hospital in Coastal Karnataka of India. World J Dent 2019; 10 (5):350-353.

DOI: 10.5005/jp-journals-10015-1663

License: CC BY-NC 4.0

Published Online: 01-10-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Aim: Oral squamous cell carcinoma (OSCC) contributes to 30% of the cancers in India. Harmful use of tobacco and alcohol is implicated in the pathogenesis of oral cancer. This study aimed at describing the tobacco consumption patterns in patients of OSCC visited in a tertiary care dental hospital in coastal Karnataka, India. Materials and methods: A cross-sectional study of 108 cases of OSCC from 2015 to 2018 was carried out in a tertiary care dental hospital. Demographic details of the patients’ sex, age, tobacco habit, and site of cancer were entered into MS Excel. Data were analyzed using SPSS version 20. The tobacco consumption pattern was expressed in percentages and proportions, and the association between the variables was determined by Chi-square (χ2) test and the Mann–Whitney U test. Results: Of the 108 cases of OSCC, 84 (77.8%) were males. The most common site of the OSCC was the buccal mucosa along the gingivobuccal sulcus, which was seen in 65 (60.20%) cases. In males, the most common type of tobacco consumed was in the smoked form, which was observed in 39 (46.4%) cases, and among females the smokeless tobacco (ST) consumption was found in 15 (62.5%) cases. Conclusion: The most common site for OSCC was the buccal mucosa along with the gingivobuccal sulcus. The most common types of tobacco consumed in patients with OSCC were smoked form in males and ST in females. Clinical significance: There is a need to work toward public awareness about the detrimental effects of tobacco practice and oral cancer screening programs, which might prevent the morbidity and mortality of OSCC in this region due to early diagnosis that is achievable.


PDF Share
  1. Coelho KR. Challenges of the oral cancer burden in India. J Cancer Epidemiol 2012;2012:1–17. DOI: 10.1155/2012/701932.
  2. Markopoulos AK. Current aspects on oral squamous cell carcinoma. Open Dent J 2012;6:126–130. DOI: 10.2174/1874210601206010126.
  3. Sankaranarayanan R, Ramadas K, Thomas G, et al. Effect of screening on oral cancer mortality in Kerala, India: a cluster-randomised controlled trial. Lancet 2005;365(9475):1927–1933. DOI: 10.1016/S0140-6736(05)66658-5.
  4. Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015;136(5):E359–E386. DOI: 10.1002/ijc.29210.
  5. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68(6):394–424. DOI: 10.3322/caac.21492.
  6. Sivapathasundharam B. Shafer's Textbook of Oral Pathology, 8th ed., Elsevier; 2016. p. 153.
  7. Jiang X, Wu J, Wang J, et al. Tobacco and oral squamous cell carcinoma: a review of carcinogenic pathways. Tob Induc Dis 2019;17:1–9.
  8. Singh MP, Kumar V, Agarwal A, et al. Clinico-epidemiological study of oral squamous cell carcinoma: a tertiary care centre study in North India. J Oral Biol Craniofac Res 2016;6(1):32–35. DOI: 10.1016/j.jobcr.2015.11.002.
  9. Mehrotra R, Pandya S, Chaudhary AK, et al. Prevalence of oral pre-malignant and malignant lesions at a tertiary level hospital in Allahabad, India. Asian Pac J Cancer Prev 2008;9(2):263–265.
  10. Nirmala CJ, Thapsey H, Murthy NS. Oral cancer and tobacco: a case control study in southern India. Int J Community Med Public Health 2017;4(12):4706–4711. DOI: 10.18203/2394-6040.ijcmph20175355.
  11. Tandon P, Dadhich A, Saluja H, et al. The prevalence of squamous cell carcinoma in different sites of oral cavity at our rural health care centre in Loni, Maharashtra – a retrospective 10-year study. Contemp Oncol (Pozn) 2017;21(2):178–183. DOI: 10.5114/wo.2017.68628.
  12. Smitha T, Mohan CV, Hemavathy S. Clinicopathological features of oral squamous cell carcinoma: a hospital-based retrospective study. J Dr NTR Univ Health Sci 2017;6(1):29–34.
  13. Krishna A, Singh RK, Singh S, et al. Demographic risk factors, affected anatomical sites and clinicopathological profile for oral squamous cell carcinoma in a North Indian population. Asian Pac J Cancer Prev 2014;15(16):6755–6760. DOI: 10.7314/APJCP.2014.15.16.6755.
  14. India Project Team of the International Cancer Genome Consortium. Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups. Nat Commun 2013;4(1):2873. DOI: 10.1038/ncomms3873.
  15. Niaz K, Maqbool F, Khan F, et al. Smokeless tobacco (paan and gutkha) consumption, prevalence, and contribution to oral cancer. Epidemiol Health 2017;39:1–11. DOI: 10.4178/epih.e2017009.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.